Injectable codeine is available for subcutaneous or intramuscular injection only; intravenous injection is contraindicated, as this may lead to nonimmune mast-cell degranulation and resulting anaphylactoid response. Codeine suppositories will also be promoted in a few nations around the world. In Eire, new restrictions arrived into effect on 1 August 2010[90] https://www.codeingil.com/