There is a release of norepinephrine with the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors from the dorsal horn to minimize afferent discomfort transmission and make analgesia. Thus, medicines like clonidine that concentrate on alpha-two receptors can influence the transmission of soreness. Clonidine is dispersed in breast milk; https://pauln811ung7.governor-wiki.com/user